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Publications

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  • Hartal-Benishay, L.; Saadi, E.; Toubiana, S.; Shaked, L.; Lalzar, M.; Abu Hatoum, O.; Tal, S.;Selig, S.; , Barki-Harrington, L., MBTPS1 regulates proliferation of colorectal cancer primarily through its action on sterol regulatory element-binding proteins
    Front Oncol. 2022 Oct 10; 12:1004014.
     

  • Saadi, E. Sood, R. Dromi, I., Srouji, R., Abu Hatoum O, Tal, S.; Barki-Harrington, L., Limited Proteolysis of Cyclooxygenase-2 Enhances Cell Proliferation Int. J. Mol. Sci. 2020, 21(9), 3195. Special Issue on Cyclooxygenase and Cancer: Fundamental Molecular Investigations.
     

  • Goncalves, I. L.; Tal, S.; Barki-Harrington, L.; Sapir, A., Conserved statin-mediated activation of a p38-MAPK pathway protects C. elegans from the cholesterol-independent effects of statins. Mol Metab 2020, 101003.
     

  • Saadi, E.; Tal, S.; Barki-Harrington, L., Substrate-inactivated cyclooxygenase-2 is disposed of by exosomes through the ER-Golgi pathway. Biochem J 2018, 475, (19), 3141-3151.
     

  • Singh, P.; Blatt, A.; Feld, S.; Zohar, Y.; #Saadi, E.; Barki-Harrington, L.; Hammond, E.; Ilan, N.; Vlodavsky, I.; Chowers, Y.; Half, E., The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression. Neoplasia 2017, 19, (3), 175-184.
     

  • Spector-Chotiner, A.; Shraga-Heled, N.; Sood, R.; Rimon, G.; Barki-Harrington, L., Prostaglandin receptor EP(1)-mediated differential degradation of cyclooxygenases involves a specific lysine residue. Biochem Biophys Res Commun 2014, 443, (2), 738-42.
     

  • Sood, R.; Ritov, G.; Boltyansky, B.; #Spector-Chotiner, A.; Richter-Levin, G.; Barki-Harrington, L., Underwater trauma causes a long-term specific increase in the expression of cyclooxygenase-2 in the ventral CA(1) of the hippocampus. Psychoneuroendocrinology 2014, 49, 62-8.
     

  • Sood, R.; Minzel, W.; Rimon, G.; Tal, S.; Barki-Harrington, L., Down-regulation of cyclooxygenase-2 by the carboxyl tail of the angiotensin II type 1 receptor. J Biol Chem 2014, 289, (45), 31473-9.
     

  • Sood, R.; Flint-Ashtamker, G.; Borenstein, D.; Barki-Harrington, L., Upregulation of prostaglandin receptor EP1 expression involves its association with cyclooxygenase-2. PLoS One 2014, 9, (3), e91018.
     

  • Harony-Nicolas, H.; Mamrut, S.; Brodsky, L.; Shahar-Gold, H.; Barki-Harrington, L.; Wagner, S., Brain region-specific methylation in the promoter of the murine oxytocin receptor gene is involved in its expression regulation. Psychoneuroendocrinology 2014, 39, 121-131.
     

  • Brender, S.; Barki-Harrington, L., Beta 1-Adrenergic receptor downregulates the expression of cyclooxygenase-2. Biochem Biophys Res Commun 2014, 451, (2), 319-21.
     

  • Sood, R.; Ritov, G.; Richter-Levin, G.; Barki-Harrington, L., Selective increase in the association of the beta2 adrenergic receptor, beta Arrestin-1 and p53 with Mdm2 in the ventral hippocampus one month after underwater trauma. Behav Brain Res 2013, 240, 26-8.
     

  • Mamrut, S.; Harony, H.; Sood, R.; Shahar-Gold, H.; Gainer, H.; Shi, Y. J.; Barki-Harrington, L.; Wagner, S., DNA methylation of specific CpG sites in the promoter region regulates the transcription of the mouse oxytocin receptor. PLoS One 2013, 8, (2), e56869.
     

  • Orenbuch, A.; Shulman, Y.; Lipstein, N.; Bechar, A.; Lavy, Y.; Brumer, E.; Vasileva, M.; Kahn, J.; Barki-Harrington, L.; Kuner, T.; Gitler, D., Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin. J Neurochem 2012, 120, (2), 248-58.
     

  • Haddad, A.; Flint-Ashtamker, G.; Minzel, W.; Sood, R.; Rimon, G.; Barki-Harrington, L., Prostaglandin EP1 receptor down-regulates expression of cyclooxygenase-2 by facilitating its proteasomal degradation. J Biol Chem 2012, 287, (21), 17214-23.
     

  • Barki-Harrington, L.; Elkobi, A.; Tzabary, T.; Rosenblum, K., Tyrosine phosphorylation of the 2B subunit of the NMDA receptor is necessary for taste memory formation. J Neurosci 2009, 29, (29), 9219-26.
     

  • Elkobi, A.; Ehrlich, I.; Belelovsky, K.; Barki-Harrington, L.; Rosenblum, K., ERK-dependent PSD-95 induction in the gustatory cortex is necessary for taste learning, but not retrieval. Nat Neurosci 2008, 11, (10), 1149-51.
     

  • Barki-Harrington, L.; Rockman, H. A., Beta-arrestins: multifunctional cellular mediators. Physiology (Bethesda) 2008, 23, 17-22.
     

  • Noma, T.; Lemaire, A.; Naga Prasad, S. V.; Barki-Harrington, L.; Tilley, D. G.; Chen, J.; Le Corvoisier, P.; Violin, J. D.; Wei, H.; Lefkowitz, R. J.; Rockman, H. A., Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. J Clin Invest 2007, 117, (9), 2445-58.
     

  • Shalom, R.; Barki-Harrington, L.; Rimon, G., Interaction between prostaglandin E2 and l-cis-diltiazem, a specific blocker of cyclic nucleotide gated channels in bovine aortic endothelial cells. Eur J Pharmacol 2006, 543, (1-3), 8-13.
     

  • El-Shewy, H. M.; Kelly, F. L.; Barki-Harrington, L.; Luttrell, L. M., Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I. Mol Endocrinol 2004, 18, (11), 2727-39.
     

  • Barki-Harrington, L.; Perrino, C.; Rockman, H. A., Network integration of the adrenergic system in cardiac hypertrophy. Cardiovasc Res 2004, 63, (3), 391-402.
     

  • Barki-Harrington, L., Oligomerisation of angiotensin receptors: novel aspects in disease and drug therapy. J Renin Angiotensin Aldosterone Syst 2004, 5, (2), 49-52.
     

  • Rapacciuolo, A.; Suvarna, S.; Barki-Harrington, L.; Luttrell, L. M.; Cong, M.; Lefkowitz, R. J.; Rockman, H. A., Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways. J Biol Chem 2003, 278, (37), 35403-11.
     

  • Barki-Harrington, L.; Rockman, H. A., Sensing heart stress. Nat Med 2003, 9, (1), 19-20.
     

  • Barki-Harrington, L.; Luttrell, L. M.; Rockman, H. A., Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo. Circulation 2003, 108, (13), 1611-8.
     

  • Barki-Harrington, L.; Bookout, A. L.; Wang, G.; Lamb, M. E.; Leeb-Lundberg, L. M.; Daaka, Y., Requirement for direct cross-talk between B1 and B2 kinin receptors for the proliferation of androgen-insensitive prostate cancer PC3 cells. Biochem J 2003, 371, (Pt 2), 581-7
     

  • Raj, G. V.; Barki-Harrington, L.; Kue, P. F.; Daaka, Y., Guanosine phosphate binding protein coupled receptors in prostate cancer: a review. J Urol 2002, 167, (3), 1458-63.
     

  • Kue, P. F.; Taub, J. S.; Barki-Harrington, L.; Polakiewicz, R. D.; Ullrich, A.; Daaka, Y., Lysophosphatidic acid-regulated mitogenic ERK signaling in androgen-insensitive prostate cancer PC-3 cells. Int J Cancer 2002, 102, (6), 572-9.
     

  • Barki-Harrington, L.; Daaka, Y., Bradykinin induced mitogenesis of androgen independent prostate cancer cells. J Urol 2001, 165, (6 Pt 1), 2121-5.

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